In 1995, Dr. Patricia Rittes, a dermatologist in Brazil, began treating patients with injections to dissolve stubborn fat deposits beneath the skin. In 2001 she published her first scientific paper detailing her management of bulging fat deposits beneath the eyes. In 2003, Dr. Franz Hasengschwandtner, an Austrian physician specializing in diet and nutritional medicine, began similar treatments but with a wider range of applications and formed Network-lipolysis. This network of physicians was taught his techniques and developed a standardized drug for injection and a standardized protocol to use the drug for fat deposits all over the body.

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